Publications

2024

+++ Zheng, K., Lyu, J., Thomas, E., Schuster, M., Sanguankiattichai, N., Ninck, S., Kaschani, F., Kaiser, M., Van der Hoorn, R. A. L. (2024) The proteome of agroinfiltrated Nicotiana benthamiana is shaped by extensive protein processing. bioRxiv

154. Chen, C., Van der Hoorn, R. A. L., and Buscaill, P. (2024) Releasing hidden MAMPs from precursor proteins in plants. Trends in Plant Sci. 29, 428-436. pubmed

152. Font Farre, M., Brown, D., König, M., Killinger, B. J., Kaschani, F., Kaiser, M., Wright, A. T., Burton, J., and van der Hoorn, R. A. L. (2024) Glutathione transferase photoaffinity labeling displays GST induction by safeners and pathogen infection. Plant Cell Physiol. 65, 128-141. pubmed

151. Schuster, M., Eisele, S., Armas-Egas, L., Kessenbrock, T., Kourelis, J., Kaiser, M., van der Hoorn, R. A. L. (2024) Enhanced late blight resistance by engineering an EpiC2B-insensitive immune protease. Plant Biotechn. J. 22, 284-286. pubmed

150. Sueldo, S., Godson, A., Kaschani, F., Krahn, D., Kessenbrock, T., Buscaill, P., Schofield, C., Kaiser, M., and Van der Hoorn, R. A. L. (2024) Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant-pathogen interface. New Phytol. 241, 394-408. pubmed.

2023

149. Homma, F., Huang, J., Van der Hoorn, R. A. L. (2023) AlphaFold-multimer predicts cross-kingdom interactions at the plant-pathogen interface. Nat. Comm. 14, 6040. pubmed

148. Longsaward. R., Sanguankiattichai, N., Viboonjun, U., and Van der Hoorn, R. A. L. (2023) Letter to the editor: Cautionary note on ribonuclease activity of recombinant PR-10 proteins. Plant Cell Physiol. 64, 847-849. pubmed

147. Barco-Antonanzas, M., Font-Farre, M., Eceiza, M. V., Gil-Monreal, M., Van der Hoorn, R. A. L., Royuela, M., and Zabalza, A. (2023) Cysteine proteases are activates in sensitive Amaranthus palmeri populations upon treatment with herbicides inhibiting amino acid biosynthesis. Physiologia Plantanum 175, e13993. pubmed

+++ Schuster, M., Eisele, S., Armas-Egas, L., Kessenbrock, T., Kourelis, J., Kaiser, M., van der Hoorn, R. A. L. (2023) Enhanced late blight resistance by engineering an EpiC2B-insensitive immune protease. bioRxiv

146. Ninck, S., Halder, V., Krahn, J., Beisser, D., Resch, S., Dodds, I., Scholtysik, R., Bormann, J., Sewald, L., Gupta, M., Hellmann, G., Bhandari, D., Morimoto, K., Buscaill, P., Van der Hoorn, R. A. L., Kaschani, F., Kaiser, M. (2023) Chemoproteomics reveals the pan-HER kinase inhibitor Neratinib to target an Arabidopsis epoxide hydrolase related to phytohormone signaling. ACE Chem. Biol. 18, 1076-1088. pubmed

+++ Homma, F., Huang, J., Van der Hoorn, R. A. L. (2023) Alphafold-multimer predicts cross-kingdom interactions at the plant-pathogen interface. bioRxiv

+++ Longsaward. R., Sanguankiattichai, N., Viboonjun, U., and Van der Hoorn, R. A. L. (2023) Cautionary note on ribonuclease activity of recombinant PR-10 proteins. bioRxiv

145. Dodds, I., Chen, C., Buscaill, P., and Van der Hoorn, R. A. L. (2023) Depletion of the NbCORE receptor drastically improves agroinfiltration productivity in older Nicotiana benthamiana plants. Plant Biotechn. J. 21, 1103-1105. pubmed

144. Kiselev, A., Camborde, L., Ossorio Carballo, L., Kaschani, F., Kaiser, M., Van der Hoorn, R. A. L. and Gaulin, E. (2023) The root pathogen Aphanomyces euteiches secretes modular proteases in Pea apoplast during host infection. Front. Plant Sci. 14, 1140101. pubmed

+++ Dodds, I., Chen, C., Buscaill, P., and Van der Hoorn, R. A. L. (2023) Depletion of the NbCORE receptor drastically improves agroinfiltration productivity in older Nicotiana benthamiana plants. bioRxiv

2022

143. Strancar, V., Van Midden, K. P., Krahn, D., Morimoto, K., Novinec, M., Funk, C., Stael, S., Schofield, C. J., Klemencic, M., and Van der Hoorn, R. A. L. (2022) Activity-based probes trap early active intermediates during metacaspase activation. iScience 25, 105247. pubmed

142. Morimoto, K., Krahn, D., Kaschani, F., Hopkinson-Woolley, D., Gee, A., Buscaill, P., Mohammed, S., Sieber, S. A., Cravatt, B. F., Schofield, C. J., and Van der Hoorn, R. A. L. (2022) Broad-range metalloprotease profiling in plants uncovers immunity provided by defence-related metalloenzyme.  New Phytol. 235, 1287-1301. pubmed

141. Jutras, P. V., Dodds, I., and Van der Hoorn, R. A. L. (2021) A bioluminescent Agrobacterium tumefaciens for imaging bacterial metabolic activity in planta. Meth. Mol. Biol. 2480, 285-293. pubmed

140. Buscaill, P., and Van der Hoorn, R. A. L. (2021) Monitoring Pseudomonas syringae growth in agroinfiltrated leaves: the ‘agromonas’ assay. Meth. Mol. Biol. 2447, 247-259. pubmed

139. Schuster, M., Paulus, J. K., Kourelis, J., and Van der Hoorn, R. A. L. (2021) Purification of His-tagged proteases from the apoplast of agroinfiltrated N. benthamiana. Meth. Mol. Biol. 2447, 53-66. pubmed

138. Morimoto, K., Stegmann, M., Kaschani, F., Mohammed, S., and Van der Hoorn, R. A. L. (2021) Cysteine reactivity profiling to unveil redox regulation in phytopathogens. Meth. Mol. Biol. 2447, 105-117. pubmed

2021

137. Abreha, K. B., Alexandersson, E., Resjö, S., Lankinen, Å., Sueldo, D., Kaschani, F., Kaiser, M., Van der Hoorn, R. A. L., Levander, F., and Andreasson, E. (2021) Leaf apoplast of field-grown potato analyzed by quantitative proteomics and activity-based protein profiling. Int. J. Mol. Sci. 22, 12033. pubmed

136. Jutras, P. V., Soldan, R., Dodds, I., Schuster, M., Preston, G. M., and Van der Hoorn, R. A. L. (2021) AgroLux: bioluminescent Agrobacterium to improve molecular pharming and study plant immunity. Plant J. 108, 600-612. pubmed

135. Van der Hoorn, R. A. L. and Klemenčič, M. (2021) Plant Proteases: from molecular mechanisms to functions in development and immunity. J. Exp. Bot. 72, 3337-3339. pubmed

134. Buscaill, P. and Van der Hoorn, R. A. L. (2021) Defeated by the nines: nine extracellular strategies to avoid MAMP recognition in plants. Plant Cell 33, 2116-2130. pubmed

133. Woude, L. V., Piotrowski, M., Klaasse, G., Paulus, J. K., Krahn, D., Ninck, S., Kaschani, F., Kaiser, M., Novák, O., Ljung, K., Bulder, S., van Verk, M., Snoek, B. L., Fiers, M., Martin, N. I., Van der Hoorn, R. A. L., Robert, S., Smeekens, S., and Van Zanten, M. (2021) The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases. Plant J. 106, 1523-1540. pubmed

132. Godson, A., and Van der Hoorn, R. A. L. (2021) The frontline of defence: meta-analysis of apoplastic proteases in plant immunity. J. Exp. Bot. 72, 3381-3394. pubmed

131. Wang, S., Xing, R., Wang, Y., Shi, H., Fu, S., Huang, J., Paulus, J. K., Schuster, M., Saunders, D. G. O., Win, J., Vleeshouwers, V., Wang, Y., Zheng, X., Van der Hoorn, R. A. L., and Dong, S. (2021) Cleavage of a pathogen apoplastic protein by plant subtilases activates host immunity. New Phytol. 229, 3424-3439. pubmed

130. Buscaill, P., Sanguankiattichai, N., Lee, Y. J., Kourelis, J., Preston, G., and Van der Hoorn, R. A. L. (2021) Agromonas: a rapid disease assay for Pseudomonas syringae growth in agroinfiltrated leaves. Plant J. 105, 831-840. pubmed

2020

129. Parry, G., Benitez-Alfonso, Y., Gibbs, D. J., Grant, M., Harper, A., Harrison, C. J., Kaiserli, E., Leonelli, S., May, S., McKim, S., Spoel, S., Turnbull, C., Van der Hoorn, R. A. L. and Murray, J. (2020) How to build an effective research network: lessons from two decades of the GARNet plant science community. J. Exp. Bot. 71, 6881-6889. pubmed

128. Kourelis, J., Malik, S., Mattinson, O., Krauter, S., Kahlon, P. S., Paulus, J. K., and Van der Hoorn, R. A. L. (2020) Evolution of a guarded decoy protease and its receptor in solanaceous plants. Nat. Comm. 11, 4393 pubmed

127. Paulus, J. K., Kourelis, J., Ramasubramanian, S., Homma, F., Godson, A., Hoerger, A. C., Hong, T. N., Krahn, D., Ossorio Carballo, L., Wang, S., Win, J., Smoker, M., Kamoun, S., Dong, S., and Van der Hoorn, R. A. L. (2020) Extracellular proteolytic cascade in tomato activates immune protease Rcr3. Proc. Nat. Acad. Sci. USA 117, 17409-17417. pubmed

126. Schuster, M., and Van der Hoorn, R. A. L. (2020) Distinct new players in processing peptide hormones during abscission. Curr. Biol. 30, R715-R717. pubmed

125. Bach-Pages, M., Homma, F., Kourelis, J., Kaschani, F., Mohammed, S., Kaiser, M., Van der Hoorn, R. A. L., Castello, A., and Preston, G. M. (2020) Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture method. Biomolecules 10, 661. pubmed

124. Minina, E. A., Staal, J., Alvarez, V. E, Berges, J. A., Berman-Frank, I., Beyaert, R., Bidle, K. D., Bornancin, F., Casanova, M., Cazzulo, J. J., Choi, C. J., Coll, N. S., Dixit, V. M., Dolinar, M., Fasel, N., Funk, C., Gallois, P., Gevaert, K., Gutierrez-Beltran, E., Hailfinger, S., Klemencic, M., Koonin, E. V., Krappmann, D., Linusson, A., Machado, M. F. M., Madeo, F., Megeney, L. A., Moschou, P. N., Mottram, J. C., Nyström, T., Osiewacz, H. D., Overall, C. M., Pandey, K. C., Ruland, J., Salvesen, G. S., Shi, Y., Smertenko, A., Stael, S., Ståhlberg, J., Suárez, M. F., Thome, M., Tuominen, H., Van Breusegem, F., Van der Hoorn, R. A. L., Vardi, A., Zhivotovsky, B., Lam, E., and Bozhkov, P. V. (2020) Classification and nomenclature of metacaspases and paracaspases: no more confusion with caspases. Mol. Cell 77, 927-929. pubmed

123. Kriechbaum, R., Ziaee E., Grünwald-Gruber, C., Buscaill, P., Van der Hoorn, R. A. L., and Castilho, A. (2020) BGAL1 depletion boosts the level of β-galactosylation of N- and O-glycans in N. benthamiana. Plant Biotechn. J. 18, 1537-1549. pubmed

122. Jutras, P. V., Dodds, I., and Van der Hoorn, R. A. L. (2020) Proteases of Nicotiana benthamiana: an emerging battle for molecular pharming. Curr. Opin. Biotechn. 61, 60-65. pubmed

2019

121. Kourelis, J., Kaschani, F., Grosse-Holz, F. M., Homma, F., Kaiser, M., and Van der Hoorn, R. A. L. (2019) A homology-guided, genome-based proteome for improved proteomics in the alloploid Nicotiana benthamiana. BMC Genomics 20, 722. pubmed

120. Morimoto, K., Cole, K. S., Kourelis, J., Witt, C. H., Brown, D., Krahn, D., Stegmann, M., Kaschani, F., Kaiser, M., Burton, J., Mohammed, S., Yamaguchi-Shinozaki, K., Weerapana, E., and Van der Hoorn, R. A. L. (2019) Triazine probes target ascorbate peroxidases in plants. Plant Physiol. 180, 1848-1859. pubmed

119. Morimoto, K., and Van der Hoorn, R. A. L. (2019) Plant Biology: proteolytic release of danger signals. Curr. Biol. 29, 378-390. pubmed

118. Buscaill, P., Chandrasekar, B., Sanguankiattichai, N., Kourelis, J., Kaschani, F., Thomas, E. L., Morimoto, K., Kaiser, M., Preston, G. M., Ichinose, Y., and Van der Hoorn, R. A. L. (2019) Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides. Science 364, 145. pubmed

117. Fernandez-Fernandez, A. D., Van der Hoorn, R. A. L., Gevaert, K., Van Beusegem, F., and Stael, S. (2019) Caught green-handed: methods for in vivo detection and visualization of protease activity. J. Exp. Bot. 70, 2125-2141. pubmed

116. Vinegra de la Torre, N., Kaschani, F., Kaiser, M., Van der Hoorn, R. A. L., Soppe, W. J. J., and Misas-Villamil, J. C. (2019) Dynamic hydrolase labelling as a marker for seed quality in Arabidopsis seeds. Biochem. J. 476, 843-857. pubmed

115. Pogorelko, P., Juvale, P., Rutter, W., Hütten, M., Maier, T., Hewezi, T., Paulus, J. K., Van der Hoorn, R. A. L., Grundler, F., Siddique, S., Lionetti, V., Zabotina, O., Baum, T. (2019) Retargeting of a defence protease by a nematode effector. Plant J. 98, 1000-1014. pubmed

114. Jutras, P. V., Grosse-Holz, F., Kaschani, F., Kaiser, M., Michaud, D., and Van der Hoorn, R. A. L. (2019) Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilising inhibitor SlCYS8 in Nicotiana benthamiana. Plant Biotechn. J. 17, 1670-1678. pubmed

113. Poret, M., Chandrasekar, B., Dechaumet S., Bouchereau, A., Kim, T. H., Lee, B. R., Macquart F., Hara-Nishimura I, Van der Hoorn, R. A. L., Avice, J. C. (2019) A genotypic comparison reveals that the improvement in nitrogen remobilisation efficiency in oilseed rape leaves is related to specific patterns of senescence-associated protease activities and phytohormones. Front Plant Sci. 10, 46. pubmed

112. Paulus, J. K. and Van der Hoorn, R. A. L. (2019) Do proteolytic cascades exist in plants? J. Exp. Bot. 70, 1997-2002. pubmed

111. Santos, R. B., Pires, A. S., Van der Hoorn, R. A. L., Schiermeyer, A., and Abranches, R. (2018) Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: a rapid method for Agrobacterium-mediated gene transfer. Plant Cell & Organ Culture 13, e1800050. pubmed

110. Ormancey, M., Thuleau P., Van der Hoorn, R. A. L., Grat, S., Testard, A., Kamal, K. Y., Boudsocq, M., Cotelle, V., and Mazars, C. (2018) Shingolipid-induced cell death in Arabidopsis is negatively regulated by the papain-like cysteine protease RD21. Plant Sci. 280, 12-17. pubmed

2018

109. Bravo Cadena, M., Preston, G. M., Van Der Hoorn, R. A. L., Flanagan, N. A., Townley, H. E., & Thompson, I. P. (2018). Enhancing cinnamon essential oil activity by nanoparticle encapsulation to control seed pathogens. Ind. Crops &Products 124, 755–764. ORA

108. Bravo Cadena, M., Preston, G. M., Van der Hoorn, R. A. L., Townley, H. E., Thompson, I. P. (2018) Species-specific antimicrobial activity of essential oils and enhancement by encapsulation in mesoporous silica nanoparticles. Ind. Crops & Products 122, 582-590. ORA

107. Van der Hoorn, R. A. L. and Rivas, S. (2018) Unravelling the role of plant proteases. New Phytol. 218, 879-881. pubmed

106. Clark, K., Franco, J., Schwizer, S., Pang, Z., Hawara, E., Liebrand, T., Pagliaccia, D., Zeng, L., Gurung, F., Wang, P., Shi, J., Wang, Y., Ancona, V., Van der Hoorn, R. A. L., Wang, N., Coaker, G., and Ma, W. (2018) An effector from the Huanglongbing-associated pathogen targets citrus proteases. Nat. Comm. 9, 1718 pubmed

105. Planas, M., Bernardo-Faura, M., Paulus, J. K., Kaschani, F., Kaiser, M., Valls, M., Van der Hoorn, R. A. L., and Coll, N. (2018) Protease activities triggered by Ralstonia solanacearum infection in susceptible and tolerant tomato lines. Mol. Cell. Proteomics 17, 1112-1125. pubmed

104. Santos, R. B., Chandrasekar, B., Mandal, M. K., Kaschani, F., Kaiser, M., Both, L., Van der Hoorn, R. A. L., Schiermeyer, A., Abranches R. (2018) Low protease content in Medicago truncatula cell cultures facilitates recombinant protein production. Biotechn. J. 13, e1800050. pubmed

103. Husaini, A. M., Morimoto, K., Chandrasekar, B., Kelly, S., Kaschani, F., Palmero, D., Jiang, J., Kaiser, M., Ahrazem, O., Overkleeft, H. S., and Van der Hoorn, R. A. L. (2018) Multiplex fluorescent activity profiling of α-glycosidases in plants. Plant Physiol. 177, 24-37. pubmed

102. Grosse-Holz, F., Madeira, L., Zahid, M. A., Songer, M., Kourelis, J., Fesenko, M., Ninck, S., Kaschani, F., Kaiser, M. and Van der Hoorn, R. A. L. (2018) Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in N. benthamiana. Plant Biotechn. J. 16, 1797-1810. pubmed

101. Thomas, E. L., and Van der Hoorn, R. A. L. (2018) Ten prominent host protease in plant-pathogen interactions. Int. J. Mol. Sci. 19, 639. pubmed

100. Kourelis, J., and Van der Hoorn, R. A. L. (2018) Defended to the nines: 25 years of resistance gene cloning identifies nine mechanisms of R protein function. Plant Cell 30, 285-299. pubmed

99. Paulus, J. K. and Van der Hoorn, R. A. L. (2018) Tricked or Trapped - two decoy mechanisms in host-pathogen interactions. PLoS Pathog. 14, e1006761. pubmed

2017

98. Zhang, H., Gannon, L., Hassall, K., Deery, M., Gibbs, D., Holdsworth, M., Van der Hoorn, R. A. L., Lilley, K., and Theodoulou, F. (2017) N-terminomics reveal control of Arabidopsis seed storage proteins and proteases by the Arg/N-end rule pathway. New Phytol. 218, 1106-1126. pubmed

97. Grosse-Holz, F., Kelly, S., Blaskowski, S., Kaschani, F., Kaiser, M., and Van der Hoorn, R. A. L. (2017) The transcriptome, extracellular proteome and active secretome of agroinfiltrated N. benthamiana uncover a large, diverse protease repertoire. Plant Biotechn. J. 16, 1068-1084. pubmed

96. Poret, M., Chandrasekar, B., Van der Hoorn, R. A. L., Coquet, L., Jouenne, T., and Avice, J. -C. (2017) Proteomic investigations of proteases involved in cotyledon senescence: a model to explore the genotypic variability of proteolysis machinery associated with nitrogen remobilisation efficiency during leaf senescence of oilseed rape. Proteomes 5, 29. pubmed

95. Teper-Bamnolker, P., Buskila, Y., Belausov, E., Wolf, D., Doron-Faigenboim, A., Ben-Dor, S., Van der Hoorn, R. A. L., Lers, A., and Eshel, D. (2017) Vacuolar processing enzyme (VPE) activates programmed cell death in the apical meristem inducing loss of apical dominance. Plant Cell & Environ. 40, 2381-2392. pubmed

+++ Lu, H., Chandrasekar, B., Oeljeklaus, J., Misas-Villamil, J. C., Wang, Z., Shindo, T., Bogyo, M., Kaiser, M., and Van der Hoorn, R. A. L. (2017) Correction in Plant Physiol. 174, 465-466 on Ref.72 link

+++ Van der Hoorn, R. A. L., Rivas, S., Wulff, B. B. H., Jones, J. D. G., and Joosten, M. H. A. J. (2017) Correction in Plant J. 90, 1212 on Ref.11 link

94. Schaller, A., Stintzi, A., Rivas, S., Serano, I., Sueldo, D. J., Van der Hoorn, R. A. L., Ramirez, V., Vera, P. (2017) From structure to function - a family portrait of plant subtilases. New Phytol. 218, 901-915. pubmed

93. Paulus, J. K., Kourelis, J., and Van der Hoorn, R. A. L. (2017) Bodyguards: pathogen-derived decoys that protect virulence factors. Trends Plant Sci. 22, 355-357. pubmed

92. Sueldo, D. J., and Van der Hoorn, R. A. L. (2017) Plant life needs cell death, but does plant cell death need Cys proteases? FEBS Lett. 284, 1577-1585. pubmed

91. Kovacs, J., Poor, P., Kaschani, F., Chandrasekar, B., Hong, T. N., Misas-Villamil, J. C., Xin, B. T., Kaiser, M., Overkleeft, H. S., Tari, I., and Van der Hoorn, R. A. L. (2017) Proteasome activity profiling uncovers alteration of catalytic beta-2 and beta-5 subunits of the stress-induced proteasome during salinity stress in tomato roots. Frontiers Plant Sci. 8, 107. pubmed

90. Misas, J. C., Van der Burgh, A., Grosse-Holz, F., Bach-Pages, M., Kaschani, F., Schilasky, S., Emon, A. E. K., Ruben, M., Kaiser, M., Overkleeft, H. S., and Van der Hoorn, R. A. L. (2017) Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections. Plant J. 90, 418-430. pubmed

89. Pruzinska, A., Shindo, T., Niessen, S., Kaschani, F., Toth, R., Millar, A. H., and Van der Hoorn, R. A. L. (2017) Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves. BMC Plant Biol. 17, 4. pubmed

88. Chandrasekar, B., Hong, T. N., and Van der Hoorn, R. A. L. (2017) Inhibitor discovery by convolution ABPP. Meth. Mol. Biol. 1491, 47-56. pubmed

2016

87. Shindo, T., Kaschani, F., Yang, F., Kovacs, J., Tian, F., Kourelis, J., Hong, T. N., Colby, T., Shabab, M., Chawla, R., Kumari, S., Ilyas, M., Hoerger, A., Alfano, J. R., and Van der Hoorn, R. A. L. (2016) Screen of non-annotated small secreted proteins of Pseudomonas syringae reveals a virulence factor that inhibits tomato immune proteases. PLoS Pathog. 12, e1005874. pubmed

86. Misas-Villamil, J. C., Van der Hoorn, R. A. L., and Doehlemann, G. (2016) Papain-like cysteine proteases as hubs in plant immunity. New Phytol. 212, 902-907. pubmed

85. Daneri-Castro, S. N., Chandrasekar, B., Grosse-Holz, F. M., Van der Hoorn, R. A. L., and Roberts, T. H. (2016) Activity-based protein profiling of hydrolytic enzymes induced by gibberellic acid in isolated aleurone layers of malting barley. FEBS Lett. 590, 2956-2962. pubmed

84. Paireder, M., Mehofer, U., Tholen, S., Porodko, A., Schahs, P., Biniossek, M. L., Van der Hoorn, R. A. L., Lenarcic, B., Novinec, M., Schilling, O., and Mach, L. (2016) The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity. Arch. Biochem. Biophys. 603, 110-107. pubmed

83. Kovacs, J., and Van der Hoorn, R. A. L. (2016) Twelve ways to confirm targets of activity-based probes in plants. Bioorg. Med. Chem. 24, 3304-3311. pubmed

+++ Van der Hoorn, R. A. L. (2016) Exploring antagonistic interactions in the plant apoplast. Biology News (Oxford University) 5, 11. pdf

82. Kaschani, F., Wei, Q., Dingemans, J., Van der Hoorn, R. A. L., Cornelis, P., and Kaiser, M. (2016) Capture of endogenously biotinylated proteins from Pseudomonas auruginosa displays unexpected regulation of LiuD upon iron nutrition. Bioorg. Med. Chem. 24, 3330-3335. pubmed

81. Kourelis, J., Van der Hoorn, R. A. L., Sueldo, D. J. (2016) Decoy engineering: the next step in resistance breeding. Trends Plant Sci. 21, 371-373. pubmed

80. Stiti, N., Chandrasekar, B., Strubl, L., Mohammed, S., Bartels, D., and Van der Hoorn, R. A. L. (2016) Nicotinamide cofactors suppress active-site labeling of aldehyde dehydrogenases. ACS Chem. Biol. 11, 1578-1586. pubmed

79. Malik, S., and Van der Hoorn, R. A. L. (2016) Inspirational decoys: a new hunt for effector targets. New Phytologist 210, 371-373. pubmed

78. Poret, M., Chandrasekar, B., Van der Hoorn, R. A. L., and Avice, J. -B. (2016) Characterization of senescence-associated protease activities in the efficient protein remobilization during leaf senescence of winter oilseed rape. Plant Sci. 246, 139-153. pubmed

77. Morimoto, K., and Van der Hoorn, R. A. L. (2016) The increasing impact of activity-based protein profiling in plant science. Plant Cell Physiol. 57, 446-461. pubmed

76. Grosse-Holz, F., and Van der Hoorn, R. A. L. (2016) Juggling jobs: roles and mechanisms of multifunctional protease inhibitors in plants. New Phytologist 57, 446-461. pubmed

75. Chandrasekar, B., and Van der Hoorn, R. A. L. (2016) Beta-galactosidases in Arabidopsis and tomato: a mini review. Biochem. Transact. 44, 150-158. pubmed PDF

2015

74. Hütten, M., Geukes, M., Misas-Villamil, J. C., van der Hoorn, R. A. L., Grundler, F. M., and Siddique, S. (2015) Activity profiling reveals changes in the diversity and activity of proteins in Arabidopsis roots in response to nematode infection. Plant Physiol Biochem. 97, 36-43. pubmed

73. Ilyas, M., Hörger, A. C., Bozkurt, T. O., Van den Burg, H. A., Kaschani, F., Kaiser, M., Belhaj, K., Smoker, M., Joosten, M. H. A. J., Kamoun, S., and Van der Hoorn, R. A. L. (2015) Functional divergence of two secreted immune proteases of tomato. Current Biol. 25, 2300-2306. pubmed

72. Lu, H., Chandrasekar, B., Oeljeklaus, J., Misas-Villamil, J. C., Wang, Z., Shindo, T., Bogyo, M., Kaiser, M., and Van der Hoorn, R. A. L. (2015) Subfamily-specific probes for Cys proteases display dynamic protease activities during seed germination. Plant Physiol. 168, 1462-1475. pubmed

71. Ting, H. M., Delatte, T. L., Kolkman, P., Misas-Villamil, J. C., Van der Hoorn, R. A. L., Bouwmeester, H. J., and Van der Krol, A. R. (2015) SNARE-RNAi results in higher terpene emission from ectopically expressed caryophyllene synthase in Nicotiana benthamiana. Mol. Plant 8, 454-466. pubmed

2014

+++ Van der Hoorn, R. A. L. (2014) Determining the fate of proteins. International Innovation 141, 22-24. PDF website

70. Chandrasekar, B., Colby, T., Emon, A. E. K., Jiang, J., Hong, T. N., Villamor, J. G., Harzen, A., Overkleeft, H. S., and Van der Hoorn, R. A. L. (2014) Broad range glycosidase activity profiling. Mol. Cell. Proteomics. 13, 2787-2800. pubmed

69. Zhang, B., Tremousaygue, D., Denancé, N., Van Esse, H. P., Hörger, A. C., Dabos, P., Goffner, D., Thomma, B. P. H. J., Van der Hoorn, R. A. L., and Tuominen, H. (2014) PIRIN2 stabilizes cysteine protease XCP2 and increases susceptibility to the vascular pathogen Ralstonia solanacearum in Arabidopsis. Plant J. 79, 1009-1019. pubmed

68. Sueldo, D., Ahmed, A., Misas-Villamil, J. C., Colby, T., Tameling, W., Joosten, M. H. A. J., and Van der Hoorn, R. A. L. (2014) Dynamic hydrolase activities precede hypersensitive tissue collapse in tomato seedlings. New Phytologist 203, 913-925. pubmed

67. Dong, S., Stam, R., Cano, L. M., Song, J., Sklenar, J., Yoshida, K., Bozkurt, T. O., Oliva, R., Liu, Z., Tian, M., Win, J., Banfield, M. J., Jones, A. M., Van der Hoorn, R. A. L., and Kamoun, S. (2014) Effector specialization in a lineage of the Irish potato famine pathogen. Science 343, 552-555. pubmed PDF Highlighted in Science, The Scientist, Science Daily, Smallholder, SeedDaily, BBSRC, PhysOrg, HispanicBusiness, Science Codex, PlantSci, RedOrbit, Vegetable Farmer, Agrotimes, Solar Daily, and Oxford.

66. Hong, T. N., and Van der Hoorn, R. A. L. (2014) DIGE-ABPP by click chemistry: pairwise comparison of serine hydrolase activities from the apoplast of infected plants. Meth. in Mol. Biol. 1127, 183-194. pubmed

2013

65. Ilyas, S., Ilyas, M., Van der Hoorn, R. A. L., and Mathur, S. (2013) Selective conjugation of proteins in mining the active proteome through click-functionalized magnetic nanoparticles. ACS Nano 7, 9655-9663. pubmed

64. Hörger, A. C., and Van der Hoorn, R. A. L. (2013) The structural basis of specific protease-inhibitor interactions at the plant-pathogen interface. Curr. Opin. Struct. Biol. 23, 843-850. pubmed

63. Zulet, A., Gil-Monreal, M., Villamor, J. G., Zabalza, A., Van der Hoorn, R. A. L., and Royuela, M. (2013) Proteolytic pathways induced by herbicides that inhibit amino acid biosynthesis. PLoS One 8, e73847. pubmed

62. Villamor, J. G., Kaschani, F., Colby, T., Oeljeklaus, J., Zhao, D., Kaiser, M., Patricelli, M. P., and Van der Hoorn, R. A. L. (2013) Profiling protein kinases and other ATP binding proteins in Arabidopsis using acyl-ATP probes. Mol. Cell. Proteomics 12, 2481-2496. pubmed

61. Misas-Villamil, J. C., Kolodziejek, I., Crabill, E., Kaschani, F., Niessen, S., Shindo, T., Kaiser, M., Alfano, J. R., and Van der Hoorn, R. A. L. (2013) Pseudomonas syringae pv. syringae uses proteasome inhibitor Syringolin A to colonize from wound infection sites. PLoS Pathogens 9, e1003281. pubmed

60. Gu, C., Shannon, A., Colby, T., Wang, Z., Shabab, M., Kumari, S., Villamor, J. G., McLaughlin, C. J., Weerapana, E., Kaiser, M., Cravatt, B. F., and Van der Hoorn, R. A. L. (2013) Chemical proteomics with sulfonyl fluoride probes reveals selective labeling of functional tyrosines in glutatione transferases. Chem. & Biol. 20, 541-548. pubmed PDF Highlighted by Dr. Verhelst in same issue!

59. Nguyen, H. M., Schippers, J. H., Goni-Ramos, O., Christoph, M. P., Dortay, H., Van der Hoorn, R. A. L., and Mueller-Roeber, B. (2013) An upstream regulator of the 26S proteasome modulates organ size in Arabidopsis thaliana. Plant J. 74, 25-36. pubmed

58. Lu, H., Wang, Z., Shabab, M., Oeljeklaus, J., Verhelst, S. H., Kaschani, F., Kaiser, M., Bogyo, M., and Van der Hoorn, R. A. L. (2013) A substrate-inspired probe monitors translocation, activation and subcellular targetting of bacterial type III effector protease AvrPphB. Chem. & Biol. 20, 168-176. pubmed Highlighted by Dr. Blum in same issue!

57. Misas-Villamil, J. C., Toenges, G., Kolodziejek, I., Sadaghiani, A. M., Kaschani, F., Colby, T., Bogyo, M., and Van der Hoorn, R. A. L. (2013) Activity profiling of vacuolar processing enzymes reveals a role for VPE during oomycete infection. Plant J. 73, 689-700. pubmed

+++ Van der Hoorn, R. A. L. (2013) RD21 Peptidase. Book chapter in Handbook of proteolytic enzymes, 3rd edition. (N. Rawings & G. Salvesen, eds.), Elsevier 2013, 1892–1896. link

 2012

56. Stolze*, S. C., Deu* E., Kaschani*, F., Li, N., Florea, B. J., Richau, K. H., Colby, T., Van der Hoorn, R. A. L., Overkleeft, H. S., Bogyo, M., and Kaiser, M. (2012) The antimalarial natural product Symplostatin 4 is a nanomolar inhibitor of the food vacuole Falcipains. Chem. & Biol. 19, 1546-1555. pubmed

55. Shannon, D., A., Gu, C., McLaughlin, C. J., Kaiser, M., Van der Hoorn, R. A. L., and Weerapana, E. (2012) Sulfonyl-fluoride analogs as activity-based probes for serine proteases. ChemBioChem, 13, 2327-2330. pubmed

54. Van der Linde, K., Mueller, A. N., Hemetsberger, C., Kaschani, F., Van der Hoorn, R. A. L., and Doehlemann, G. (2012) The maize cystatin CC9 interacts with apoplastic cysteine proteases. Plant Sign. Behav. 7, 1397-1401. pubmed

53. Hörger, A. C., Ilyas, M., Stephan, W., Tellier, A., Van der Hoorn*, R. A. L. and Rose*, L. E. (2012) Balancing selection at the tomato RCR3 guardee gene family maintains variation in strength of pathogen defense. PLoS Genetics 8, e1002813. pubmed

52. Lozano-Torres, J. L., Wilbers, R. H. P., Gawronski, P., Boshoven, J. C., Finkers-Tomczak, A., Cordewener, J. H. G., America, A. H. P., Overmars, H. A., Van 't Klooster, J. W., Baranowski, L., Sobczak, M., Ilyas, M., Van der Hoorn, R. A. L., Schots, A., De Wit, P. J. G. M., Bakker, J., Goverse, A., and Smant, G. (2012) Dual disease resistance mediated by immune receptor Cf-2 in tomato require a common virulence target of a fungus and a nematode. Proc. Nat. Acad. Sci. USA 109, 10119-10124. pubmed

51. Richau, K., Kaschani, F., Verdoes, M., Pansuriya, T. C., Niessen, S., Stüber, K., Overkleeft, H. S., Bogyo, M., and Van der Hoorn, R. A. L. (2012) Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics. Plant Physiol. 158, 1583-1599. pubmed

50. Van der Linde, K., Hemetsberger, C., Kastner, C., Kaschani, F., Van der Hoorn, R. A. L., Kumlehn, J., and Doehlemann, G. (2012) A maize cystatin suppresses host immunity by inhibition of apoplastic cysteine proteases. Plant Cell 24, 1285-1300. pubmed

49. Kaschani, F., Clerc, J., Krahn, D., Ottmann, C., Bier, D., Ngoc Hong, T., Ottmann, C., Niessen, S., Colby, T., Van der Hoorn, R. A. L., and Kaiser, M. (2012) Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenases. Angew. Chem. Int. Ed. 51, 5230-5233. pubmed

48. Gu, C., Shabab, M., Strasser, R., Wolters, P. J., Shindo, T., Niemer, M., Kaschani, F., Mach, L., and Van der Hoorn, R. A. L. (2012) Post-translational regulation and trafficking of the granulin-containing protease RD21 of Arabidopsis thaliana. PLoS One 7, e32422. pubmed PDF

47. Ottmann, C., Van der Hoorn, R. A. L., and Kaiser, M. (2012) The impact of plant-pathogen studies on medicinal drug discovery. Chem. Soc. Rev. 41, 3168-3178 pubmed

46. Kaschani, F., Gu, C., and Van der Hoorn, R. A. L. (2012) Activity-based protein profiling of infected plants. Meth. Mol. Biol. 835, 47-59. pubmed PDF

45. Shindo, T., Misas-Villamil, J. C., Hörger, A., Song, J., and Van der Hoorn, R. A. L. (2012) A role in immunity for Arabidopsis cysteine protease RD21, the ortholog of the tomato immune protease C14. PLoS One 7, e29317. pubmed

44. Kaschani, F., Nickel, S., Pandey, B., Cravatt, B.F., Kaiser, M., and Van der Hoorn, R. A. L. (2012) Selective inhibition of plant serine hydrolases by agrochemicals revealed by competitive ABPP. Bioorg. Med. Chem. 20, 597-600. pubmed PDF

43. Lenger, J., Kaschani, F., Lenz, T., Dalhoff, C., Villamor, J. G., Koster, H., Sewald, N., and Van der Hoorn, R. A. L. (2012) Labeling and enrichment of Arabidopsis thaliana matrix metalloproteases using an active-site directed, marimastat-based photoreactive probe. Bioorg. Med. Chem. 20, 592-596. pubmed 

42. Nickel, S., Kaschani, F., Colby, T., Van der Hoorn, R. A. L., and Kaiser, M. (2012) A para-nitrophenol phosphonate probe labels distinct serine hydrolases in Arabidopsis. Bioorg. Med. Chem. 20, 601-606. pubmed

+++ Van der Hoorn, R. A. L., Gu, C., Kaschani, F., Misas-Villamil, J. C., Richau, K., Kolodziejek, I., Moquet, F., Malliart, C., Berthet, X., Goni-Ramos, O., Ellul, P. (2012) Seed trait prediction by activity-based protein profiling. WO Patent 2012100963

2011 

41. Bozkurt, T., Schornack, S., Win, J., Shindo, T., Ilyas, M., Oliva, R., Cano, L. M., Jones, A. M. E., Huitema, E., Van der Hoorn, R. A. L., and Kamoun, S. (2011) Phytophthora infestans effector AVRblb2 prevents secretion of a plant immune protease at the haustorial interface. Proc. Natl. Acad. Sci USA. 108, 20832-20837. pubmed

40. Van der Hoorn, R. A. L., and Kaiser, M. (2012) Probes for activity-based profiling of plant proteases. Physiol. Plantarum 145, 18-27. pubmed

39. Van der Hoorn, R. A. L., Colby, T., Nickel, S., Richau, K., Schmidt, J., and Kaiser, M. (2011) Mining the active proteome of Arabidopsis thaliana. Frontiers Plant Physiol. 2, 89. pubmed

38. Kumari, S., and Van der Hoorn, R. A. L. (2011) A structural biology perspective on bioactive small molecules and their plant targets. Curr. Opin. Plant Biol. 14, 480-488. pubmed

37. Misas-Villamil*, J. C., Kolodziejek*, I., and Van der Hoorn, R. A. L. (2011) Pseudomonas syringae colonizes distant tissues in Nicotiana benthamiana through xylem vessels. Plant J. 67, 774-782. pubmed

36. Kaschani, F., and Van der Hoorn, R. A. L. (2011) A model of the C14-EPIC complex indicates hotspots for a protease-inhibitor arms race in the oomycete-potato interaction. Plant Signal. Behav. 6, 1-4. pubmed

35. Kolodziejek*, I., Misas-Villamil*, J. C., Kaschani, F., Clerc, J., Gu, C., Krahn, D., Niessen, S., Verdoes, M., Willems, L. I., Overkleeft, H. S., Kaiser, M. and Van der Hoorn, R. A. L. (2011) Proteasome activity imaging and profiling characterizes bacterial effector Syringolin A. Plant Physiol. 155, 477-489. pubmed

34. Richau, K. H., and Van der Hoorn, R. A. L. (2011) Studies on plant-pathogen interactions using activity-based proteomics. Curr. proteomics 7, 328-336. website

33. Lenz, H. D., Haller, E., Melzer, E., Kober, K., Wurster, K., Stahl, M., Bassham, D. C., Vierstra, R. D., Parker, J. E., Bautor, J., Molina, A., Escudero, V., Shindo, T., Van der Hoorn, R. A. L., Gust, A. A., and Nuernberger, T. (2011) Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. Plant J. 66, 818-830. pubmed

2010

32. Kaschani, F., Shabab, M., Bozkurt, T., Shindo, T., Schornack, S., Gu, C., Ilyas, M., Win, J., Kamoun, S., and Van der Hoorn, R. A. L. (2010) An effector-targeted protease contributes to defense against Phytophthora infestans and is under diversifying selection in natural hosts. Plant Physiol. 154, 1794-1804. pubmed

+++ Van der Hoorn, R. A. L., Gu, C., Ilyas, M., Kolodziejek, I., Kumari, S., Misas-Villamil, J. C., Pruzinska, A., Richau, K. H., Shabab, M., Shindo, T., Wang, Z. and Kaschani, F. (2010) Mining the active proteome in plant-pathogen interactions. In: Biology of Plant-Microbe Interactions, Volume 7. H. Antound, T. Avis, L. Brisson, D. Prevost, and M. Trepanier, eds. International Society for Molecular Plant-Microbe Interactions, St. Paul, MN.

31. Kolodziejek, I., and Van der Hoorn, R. A. L. (2010) Mining the active plant proteome in plant science and biotechnology. Curr. Opin. Biotechn. 21, 225-233. pubmed

30. Gu, C., Kolodziejek, I., Misas-Villamil, J. C., Shindo, T., Colby, T., Verdoes, M., Richau, K. H., Schmidt, J., Overkleeft, H. S., and Van der Hoorn, R. A. L. (2010) Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defence-induced proteasome activities. Plant J. 62, 160-170. pubmed PDF

29. Toth, R., and Van der Hoorn, R. A. L. (2010) Emerging principles in plant chemical genetics. Trends in Plant Sci. 15, 81-88. pubmed

2009

28. Kaschani*, F., Gu*, C., Niessen, S., Hoover, H., Cravatt, B. F., and Van der Hoorn, R. A. L. (2009) Diversity of Serine hydrolase activities of non-challenged and Botrytis-infected Arabidopsis thaliana. Mol. Cell. Proteomics 8, 1082-1093 pubmed PDF

27. Song, J., Win, J., Tian, M., Schornack, S., Kaschani, F., Muhammad, I., Van der Hoorn, R. A. L., and Kamoun, S. (2009) Apoplastic effectors secreted by two unrelated eukaryotic plant pathogens target the tomato defense protease Rcr3. Proc. Natl. Acad. Sci. USA 106, 1654-1659. pubmed

26. Hogenhout, S. A., Van der Hoorn, R. A. L., Terauchi, R., and Kamoun, S. (2009) Emerging concepts in effector biology of plant-associated organisms. Mol. Plant-Microbe Interact. 22, 115-122. pubmed

25. Kaschani, F., Verhelst, S. H. L., Van Swieten, P. F., Verdoes, M., Wong, C. -S., Wang, Z., Kaiser, M., Overkleeft, H. S., Bogyo, M., and Van der Hoorn, R. A. L. (2009) Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using 'click-chemistry'. Plant J. 57, 373-385. pubmed PDF

+++ Van der Hoorn, R. A. L. (2009) Activity-based protein profiling of Cys proteases. Book chapter in: Chemical Biology. Learning through case studies. (H. Waldmann, P. Janning, eds.) Wiley VCH, 2009, pp69-78.

2008

24. Van der Hoorn, R. A. L., and Kamoun, S. (2008) From guard to decoy: a new model for perception of plant pathogen effectors. Plant Cell 20, 2009-2017. pubmed

23. Wang*, Z., Gu*, C., Colby, T., Shindo, T., Balamurugan, R., Waldmann, H., Kaiser, M., and Van der Hoorn, R. A. L. (2008) Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana. Nat. Chem. Biol. 4, 557-563. pubmed  Highlighted by Carrico I., Nat. Chem. Biol. (2008) pressrelease (German)

22. Misas-Villamil, J. C., and Van der Hoorn, R. A. L. (2008) Enzyme-inhibitor interactions at the plant-pathogen interface. Curr. Opin. Plant Biol. 11, 380-388. pubmed

21. Shabab*, M., Shindo*, T., Gu, C., Kaschani, F., Pansuriya, T., Chintha, R., Harzen A., Colby, T., Kamoun, S., and Van der Hoorn, R. A. L. (2008) Fungal effector protein AVR2 targets diversifying defence-related Cys proteases of tomato. Plant Cell 20, 1169-1183. pubmed

20. Van der Hoorn, R. A. L. (2008) Plant proteases: from phenotypes to molecular mechanisms. Ann. Rev. Plant Biol. 59, 191-223. pubmed PDF

19. Shindo, T., and Van der Hoorn, R. A. L. (2008) Papain-like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders. Mol. Plant Pathol. 9, 119-125. MPP

2007

18. Gilroy, E., Hein, I., Van der Hoorn, R. A. L., Boevink, P., Venter, E., McLellan, H., Kaffarnik, F., Hrubikova, K., Shaw, J., Holeva, M., Lopez, E., Hidalgo, O., Pritchard, L., Loake, G., Lacomme, C., and Birch, P. (2007) Involvement of cathepsin B in the plant disease resistance hypersensitive response. Plant J. 52, 1-13. pubmed

+++ Kaschani, F., and Van der Hoorn, R. A. L. (2007) Anwendung von activity-based proteomics zur Analyse von Pflanzen-Pathogen Interaktionen. Max Planck Society Yearbook 2007, 625-629. link

17. Kaschani, F., and Van der Hoorn, R. A. L. (2007) Small molecule approaches in plants. Curr. Opin. Chem. Biol. 11, 88-98. pubmed

16. Tian, M., Win, J., Song, J., Van der Hoorn, R. A. L., Van der Knaap, E., and Kamoun, S. (2007) A Phytophthora infestans cystatin-like protein interacts with and inhibits a tomato papain-like apoplastic protease. Plant Physiol. 143, 364-277. pubmed

 2005

15. Rooney*, H., Van ’t Klooster*, J., Van der Hoorn, R. A. L., Joosten, M. H. A. J., Jones, J. D. G., and De Wit, P. J. G. M. (2005) Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance. Science 308, 1783-1789. pubmed
Recommended in faculty 1000.

14. Van der Hoorn*, R. A. L., Wulff*, B., Rivas*, S., Durrant, M. C., Van der Ploeg, A., De Wit, P. J. G. M., and Jones, J. D. G. (2005) Structure-function analysis of Cf-9, a receptor-like protein with extracytoplasmic leucine-rich repeats. Plant Cell 17, 1000-1015. pubmed

2004

13. Van der Hoorn, R. A. L. and Jones, J. D. G. (2004) The plant proteolytic machinery and its role in defence. Curr. Opin. Plant Biol. 7, 400-407. pubmed

12. Van der Hoorn, R. A. L., Leeuwenburgh, M. A, Bogyo, M., Joosten, M. H. A. J., and Peck, S. C. (2004) Activity profiling of papain-like cysteine proteases in plants. Plant Physiol. 135, 1170-1178. pubmed Highlighted in faculty 1000.

2003

11. Van der Hoorn, R. A. L., Rivas, S., Wulff, B. B. H., Jones, J. D. G., and Joosten, M. H. A. J. (2003). Rapid migration in gel filtration of the Cf-4 and Cf-9 resistance proteins is an intrinsic property of Cf proteins and not because of their association with high-molecular-weight proteins. Plant J. 35, 305-315. pubmed

2002

10. Van der Hoorn, R. A. L., De Wit, P. J. G. M., and Joosten, M. H. A. J. (2002) Balancing selection favors guarding resistance proteins. Trends Plant Sci. 6, 67-71. pubmed

2001

9. Van der Hoorn, R. A. L., Roth, R., and De Wit, P. J. G. M. (2001) Identification of distinct specificity determinants in resistance protein Cf-4 allows construction of a Cf-9 mutant that confers recognition of avirulence protein AVR4. Plant Cell 13, 273-285. pubmed

8. Van der Hoorn, R. A. L., Van der Ploeg, A., De Wit, P. J. G. M., and Joosten, M. H. A. J. (2001) The C-terminal dilysine motif for targeting to the endoplasmic reticulum is not required for Cf-9 function. Mol. Plant-Microbe Interact. 14, 412-415. pubmed

7. Van der Hoorn*, R. A. L., Kruijt*. M., Roth, R., Brandwagt, B. F., Joosten, M. H. A. J., and De Wit, P. J. G. M. (2001) Intragenic recombination generated two distinct Cf genes that mediate AVR9 recognition in the natural population of Lycopersicon pimpinellifolium. Proc. Natl. Acad. Sci. USA 98, 10493-10498. pubmed

6. Joosten, M. H. A. J., Brandwagt, B. F., Van der Hoorn, R. A. L., De Jong, C. F., Van 't Klooster, J. W., De Kock, M. J. D., Kruijt, M., Luderer, R., Takken, F. L. W., Westerink, N. and De Wit, P. J. G. M. (2001) The role of secreted proteins of the pathogenic fungus Cladosporium fulvum in (a) virulence on its host, tomato. Phytopathology 91, S161.

5. De Wit, P. J. G. M., Brandwagt, B. F., Van den Burg, H. A., Cai, X., Van der Hoorn, R. A. L., De Jong, C. F., Van't Klooster, J., De Kock, M. J. D., Kruijt, M., Lindhout, W. H., Luderer, R., Takken, F. L. W., Westerink, N., Vervoort, J. J. M., Joosten, M. H. A. J. (2001) The molecular basis of co-evolution between Cladosporium fulvum and tomato. Anton. Leeuw. Int. J. G. 81, 409-412. pubmed

2000

4. Van der Hoorn, R. A. L., Laurent, F., Roth, R., and De Wit, P. J. G. M. (2000) Agroinfiltration is a versatile tool that facilitates comparative analysis of Avr9/Cf-9-induced and Avr4/Cf-4-induced necrosis. Mol. Plant-Microbe Interact. 13, 439-446. pubmed

3. Luderer, R., Rivas, S., Nürnberger, T., Mattei, B., Van den Hooven, H. W., Van der Hoorn, R. A. L., Romeis, T., Wehrfritz, J. M., Blume, B., Nennstiel, D., Zuidema, D., Vervoort, J., De Lorenzo, G., Jones, J. D. G., De Wit, P. J. G. M., and Joosten, M. H. A. J. (2000) No evidence for binding between resistance gene product Cf-9 of tomato and avirulence gene product AVR9 of Cladosporium fulvum. Mol. Plant-Microbe Interact. 14, 867-876. pubmed

2. Stam, M., De Bruin, R., Van Blokland, R., Van der Hoorn, R. A. L., Mol, J. N. M., and Kooter, J. M. (2000) Distinct features of post-transcriptional gene silencing by antisense transgenes in single copy and inverted T-DNA repeat loci. Plant J. 21, 27-42. pubmed

+++ Joosten, M. H. A. J., Cai, X. Z., Van der Hoorn, R. A. L., De Jong, C. F., De Kock, M., Lauge, R., Luderer, R., Roth, R., Takken, F., Vossen, P., Weide, R., Westerink, N., De Wit, P. J. G. M. (2000) Fungal (A)virulence and host resistance in the Cladosporium fulvum-tomato interaction. Book chapter in: Biology of Plant-Microbe Interactions. Vol.2, APS-PRESS 2000, 29-34.

1997

1. Stam, M., De Bruin, R., Kenter, S., Van der Hoorn, R. A. L., Van Blokland, R., Mol, J. N. M., and Kooter, J. M. (1997) Post-transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats. Plant J. 12, 63-82. pubmed

*, equal contibutions; underlined, teammember during contribution