Plant Chemetics Laboratory
University of Oxford
Welcome to the Plant Chemetics Laboratory
The Plant Chemetics lab investigates the molecular mechanisms underpinning host manipulation by plant pathogens, with a particular focus on apoplast manipulation of Solanaceous plants by bacterial microbes. Our research activities also aim at improved molecular pharming of secreted (glyco)proteins through the depletion of immune responses and by removing secreted proteases. Unique is our approach to display protein activities by pioneering activity-based protein profiling (ABPP), and other chemical proteomic technologies, which offers exciting platforms for collaborations. Please contact us if you are interested to join or collaborate!
News
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January 2022
Happy 2022! New year dinner at Somerville college. Looking back to a successful 2021 and forward to an exciting 2022. Cheers! -
December 2021
Maria has submitted her D. Phil. thesis on activity-based labeling of cytochrome P450s and glutathione transferases and successfully defended her work at the D. Phil. viva. Congrants Maria!!! -
October 2021
AgroLux: a luminescent strain of Agrobacterium tumefaciens to monitor Molecular Pharming and Plant Immunity in agroinfiltrated leaves. -
September 2021
A 4-day labretreat to Somerset. A lot of scientific creativity, good hikes and good gaming! -
May 2021
Tee has submitted his D. Phil. thesis and successfully defended his work on the biosynthesis and identify of the BGAL1 inhibitor during the D. Phil. viva. Congrats, Tee!!! -
May 2021
Defeated by the nines: nine extracellular strategies to avoid MAMP recognition in plants. An impressive review on how plant pathogens avoid recognition in the plant apoplast, published in The Plant Cell. Read here more about the first author Pierre Buscaill. -
March 2021
ERC Advanced grant! We will soon be spending 2,5 million euro to explore the plant-pathogen interface with chemical proteomics! Postdoc positions will be advertised soon! -
March 2021
Special Issue on Plant Proteases with an impressive review by Alice Godson with a meta-analysis of secreted immune proteases in plants!