Plant Chemetics Laboratory
University of Oxford
Welcome to the Plant Chemetics Laboratory
The Plant Chemetics lab investigates the molecular mechanisms underpinning host manipulation by plant pathogens, with a particular focus on apoplast manipulation of Solanaceous plants by bacterial microbes. Our research activities also aim at improved molecular pharming of secreted (glyco)proteins through the depletion of extracellular proteases. Unique is our approach to display protein activities by pioneering activity-based protein profiling (ABPP), a powerful functional proteomics technology that offers an exciting platform for collaborations. Please contact us if you are interested to join or collaborate!
News
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May 2021
Defeated by the nines: nine extracellular strategies to avoid MAMP recognition in plants. An impressive review on how plant pathogens avoid recognition in the plant apoplast, published in The Plant Cell. Read here more about the first author Pierre Buscaill. -
March 2021
ERC Advanced grant! We will soon be spending 2,5 million euro to explore the plant-pathogen interface with chemical proteomics! Postdoc positions will be advertised soon! -
March 2021
Special Issue on Plant Proteases with an impressive review by Alice Godson with a meta-analysis of secreted immune proteases in plants! -
December 2020
Emma has submitted her D. Phil. thesis and successfully defended this during her viva. After she has made the minor corrections we can call her Dr. Thomas!!! -
September 2020
Evolution of a guarded decoy published in Nature Communications. An impressive piece of research, spear-headed by Jiorgos Kourelis. -
July 2020
First proteolytic cascade in plants: Subtilase P69B of tomato activates immune protease Rcr3. Wonderful protein biochemistry uncovered by Judith Paulus! See more in PNAS. -
April 2020
A new BBSRC grant with Gail Preston to identify the BGAL1 inhibitor produced by Pseudomonas syringae! Exciting years ahead!
